Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.67 |
| ▸ | CA2 | P00918 | 5/20 | 0.67 |
| ▸ | CA9 | Q16790 | 5/20 | 0.67 |
| ▸ | CA12 | O43570 | 4/20 | 0.67 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 6/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232636 | 0.83 | CA1 (0.70) | CA1CA2CA9CA12KDR | |
| SCHEMBL9232639 | 0.82 | CA1 (0.68) | CA1CA2CA9CA12KDR | |
| SCHEMBL9236170 | 0.81 | SMN1; SMN2 (0.53) | CA1CA2CA9CA12KDR | |
| SCHEMBL2555263 | 0.81 | CA1 (0.78) | CA1CA2CA9CA12KDR | |
| SCHEMBL15325008 | 0.80 | CA1 (1.00) | CA1CA2CA9CA12KDR | |
| SCHEMBL11830691 | 0.78 | CA1 (0.42) | CA1CA2CA9CA12KDR | |
| SCHEMBL11729587 | 0.78 | LMNA (0.51) | CA1CA2CA9CA12KDR | |
| SCHEMBL13849447 | 0.76 | CA1 (0.68) | CA1CA2CA9CA12KDR | |
| SCHEMBL31018735 | 0.73 | CA1 (0.65) | CA1CA2CA9CA12KDR | |
| SCHEMBL11826091 | 0.73 | CA1 (0.55) | CA1CA2CA9CA12KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632040-A1 | Antibacterial imidazole derivatives | Takeda Chemical Industries, Ltd. (JP) | 1995-01-04 | — | — | EP | disclosed |