Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 12/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.38 |
| ▸ | GLI1 | P08151 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826262 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHRCTSBCTSSCTSK | |
| SCHEMBL10208151 | 0.89 | ALDH1A1 (0.35) | ALDH1A1TSHRCTSBCTSSCTSK | |
| SCHEMBL13863235 | 0.89 | ALDH1A1 (0.35) | ALDH1A1TSHRCTSBCTSSCTSK | |
| SCHEMBL18991404 | 0.89 | GABRR1 (0.40) | ALDH1A1TSHRCTSBCTSSCTSK | |
| SCHEMBL3140213 | 0.89 | GABRR1 (0.40) | ALDH1A1TSHRCTSBCTSSCTSK | |
| SCHEMBL18992125 | 0.87 | EPHX1 (0.37) | ALDH1A1TSHRCTSBCTSSCTSK | |
| SCHEMBL24343994 | 0.85 | CHRM2 (0.39) | TSHRCTSBCTSSCTSKDPP4 | |
| SCHEMBL10161016 | 0.83 | DPP4 (0.32) | ALDH1A1TSHRCTSBCTSSCTSK | |
| SCHEMBL10161007 | 0.83 | DPP4 (0.32) | ALDH1A1TSHRCTSBCTSSCTSK | |
| SCHEMBL19156993 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956386-A | Cis-N,N,N',N'-tetramethylcyclopropane-1,2-dicarboxamide and use thereof | MONSANTO COMPANY (US) | 1976-05-11 | — | — | US | claimed |
| US-3956386-A | Cis-N,N,N',N'-tetramethylcyclopropane-1,2-dicarboxamide and use thereof | MONSANTO COMPANY (US) | 1976-05-11 | — | — | US | disclosed |
| US-3956386-A | Cis-N,N,N',N'-tetramethylcyclopropane-1,2-dicarboxamide and use thereof | MONSANTO COMPANY (US) | 1976-05-11 | — | — | US | disclosed |
| US-3956386-A | Cis-N,N,N',N'-tetramethylcyclopropane-1,2-dicarboxamide and use thereof | MONSANTO COMPANY (US) | 1976-05-11 | — | — | US | disclosed |