SCHEMBL118264

SCHEMBL118264

O=C1CCC(=O)CC(=O)C1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.43
TRIM24 O15164 2/20 0.40
TRIM33 Q9UPN9 2/20 0.40
ALDH1A1 P00352 1/20 0.38
CYP1A2 P05177 1/20 0.37
CFTR P13569 1/20 0.32
GOPC Q9HD26 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8998614 0.96 CYP2A6 (0.41) CYP2A6TRIM24TRIM33ALDH1A1CYP1A2
SCHEMBL73117 0.95
SCHEMBL9989026 0.95
SCHEMBL501836 0.91
SCHEMBL9066344 0.91 TRIM24 (0.50) CYP2A6TRIM24TRIM33ALDH1A1CYP1A2
SCHEMBL9627922 0.91
SCHEMBL8022297 0.91 TRIM24 (0.50) CYP2A6TRIM24TRIM33ALDH1A1CYP1A2
SCHEMBL1431864 0.85
SCHEMBL232122 0.85
SCHEMBL11352253 0.84 TRIM24 (0.53) CYP2A6TRIM24TRIM33ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3160 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-20250271447-A1 MULTIPLEXING HOMOCYSTEINE AND CYSTEINE IN FIRST-TIER SCREENING ASSAYS US HEALTH (US) 2025-08-28 US claimed
US-20250258146-A1 QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP HUMAN METABOLOMICS INSTITUTE INC. (CN) 2025-08-14 US claimed
CN-119746835-A Bowl-shaped nanocomposite for capturing exosomes and preparation method and application thereof 北京大学 2025-04-04 CN claimed
WO-2025068213-A1 USE OF A MARKER SET FOR DETERMINING THE RISK OF HAVING OR DEVELOPING BLADDER CANCER NUMARES AG (DE) 2025-04-03 WO claimed
US-20250073321-A1 Modulation of Oxidative Stress and Amino Acid Metabolism for the Treatment or Prevention of Diseases and Disorders UNIV NEW YORK (US) 2025-03-06 US claimed
EP-4511658-A1 MULTIPLEXING HOMOCYSTEINE AND CYSTEINE IN FIRST-TIER SCREENING ASSAYS The United States of America, as represented by The Secretary, Department of Health and Human Services (US) 2025-02-26 EP claimed
CN-118155825-A Diagnosis and treatment of rhabdomyolysis-induced acute kidney injury 上海美瑞科生物科技有限公司 2024-06-07 CN claimed
CN-116386716-B Metabolomics and methods for gastric cancer diagnosis 浙江省肿瘤医院 2024-03-15 CN claimed
CN-117074589-A Method for detecting succinylacetone, amino acid and carnitine in maternal amniotic fluid 山东英盛生物技术有限公司 2023-11-17 CN claimed
US-5104898-A Administering succinylacetone(4,6-dioxoheptanoic acid) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1992-04-14 US claimed
EP-0413757-A4 METHOD FOR TREATING AUTOIMMUNE DISEASE USING SUCCINYLACETONE US HEALTH (US) 1991-06-12 EP claimed
WO-1991004734-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING 4,6-TIOXOHEPTANOIC ACID OR ITS DERIVATIVES CETUS CORPORATION (US) 1991-04-18 WO claimed
WO-1991003455-A1 PROCESS FOR MAKING SUCCINYL ACETONE CETUS CORPORATION (US) 1991-03-21 WO claimed
EP-0413757-A1 METHOD FOR TREATING AUTOIMMUNE DISEASE USING SUCCINYLACETONE THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1991-02-27 EP claimed
WO-1991001726-A1 METHOD OF PREVENTING GRAFT REJECTION IN SOLID ORGAN TRANSPLANTATION THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) 1991-02-21 WO claimed
US-4895872-A TREATING HYPERACTIVE IMMUNE SYSTEMS; AUTOIMMUNE AND GRAFT/HOST DISEASES CETUS CORPORATION (US) 1990-01-23 US claimed
WO-1990000049-A2 IMMUNOSUPPRESSIVE ANALOGUES AND DERIVATIVES OF SUCCINYLACETONE CETUS CORPORATION (US) 1990-01-11 WO claimed
WO-1989010742-A1 METHOD FOR TREATING AUTOIMMUNE DISEASE USING SUCCINYLACETONE THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH (US) 1989-11-16 WO claimed
US-4670467-A SUCCINYLACETONE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1987-06-02 US claimed