Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118264 | 0.96 | CYP2A6 (0.43) | CYP2A6TRIM24TRIM33ALDH1A1CYP1A2 | |
| SCHEMBL9627922 | 0.96 | — | — | |
| SCHEMBL9989026 | 0.91 | — | — | |
| SCHEMBL73117 | 0.91 | — | — | |
| SCHEMBL501836 | 0.87 | — | — | |
| SCHEMBL9066344 | 0.87 | TRIM24 (0.50) | CYP2A6TRIM24TRIM33ALDH1A1CYP1A2 | |
| SCHEMBL8022297 | 0.87 | TRIM24 (0.50) | CYP2A6TRIM24TRIM33ALDH1A1CYP1A2 | |
| SCHEMBL1431864 | 0.82 | — | — | |
| SCHEMBL232122 | 0.82 | — | — | |
| SCHEMBL9413765 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484395-B1 | METHOD OF PREVENTING GRAFT REJECTION IN SOLID ORGAN TRANSPLANTATION | US HEALTH (US) | 1996-09-11 | — | — | EP | claimed |
| EP-0484395-A4 | METHOD OF PREVENTING GRAFT REJECTION IN SOLID ORGAN TRANSPLANTATION | US HEALTH (US) | 1992-08-12 | — | — | EP | claimed |
| EP-0484395-A1 | METHOD OF PREVENTING GRAFT REJECTION IN SOLID ORGAN TRANSPLANTATION. | US HEALTH (US) | 1992-05-13 | — | — | EP | claimed |
| US-5104898-A | Administering succinylacetone(4,6-dioxoheptanoic acid) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-04-14 | — | — | US | claimed |
| WO-1991001726-A1 | METHOD OF PREVENTING GRAFT REJECTION IN SOLID ORGAN TRANSPLANTATION | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1991-02-21 | — | — | WO | claimed |
| EP-0484395-B1 | METHOD OF PREVENTING GRAFT REJECTION IN SOLID ORGAN TRANSPLANTATION | US HEALTH (US) | 1996-09-11 | — | — | EP | disclosed |