Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11829172 | 0.91 | HTR2A (0.42) | HTR2AALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL11824081 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11826752 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11828639 | 0.84 | ALDH1A1 (0.57) | HTR2AALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL11824715 | 0.83 | MAPT (0.41) | HTR2AALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL11823112 | 0.83 | MAPT (0.41) | HTR2AALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL11818955 | 0.81 | MAPT (0.46) | HTR2AALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL11826064 | 0.80 | MAPT (0.54) | HTR2AALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL11822814 | 0.80 | KMT2A (0.41) | HTR2AALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL11821141 | 0.79 | MAPT (0.35) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975384-A | ANTITHROMBOTICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-08-17 | — | — | US | disclosed |