Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10196673 | 0.86 | DRD2 (0.54) | DRD2CARM1PRMT6SLC18A3DRD4 | |
| SCHEMBL8351025 | 0.84 | DRD2 (0.75) | DRD2SLC6A4SIGMAR1 | |
| SCHEMBL3591082 | 0.83 | DRD2 (0.55) | DRD2SLC18A3DRD3SIGMAR1 | |
| SCHEMBL22537717 | 0.83 | DRD2 (0.54) | DRD2CARM1PRMT6SLC18A3DRD4 | |
| SCHEMBL22171222 | 0.83 | SLC18A3 (0.70) | DRD2CARM1PRMT6SLC18A3DRD4 | |
| SCHEMBL11835997 | 0.83 | DRD2 (0.73) | DRD2SLC18A3DRD4DRD3 | |
| SCHEMBL22537568 | 0.83 | DRD2 (0.54) | DRD2CARM1PRMT6SLC18A3DRD4 | |
| SCHEMBL10360724 | 0.82 | SLC18A3 (0.69) | DRD2CARM1PRMT6SLC18A3PRMT3 | |
| SCHEMBL81641 | 0.80 | DRD2 (0.54) | DRD2CARM1PRMT6SLC18A3DRD4 | |
| SCHEMBL81936 | 0.80 | DRD2 (0.55) | DRD2CARM1PRMT6SLC18A3TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3995045-A | ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1976-11-30 | — | — | US | disclosed |