Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | MYOC | Q99972 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | MGLL | Q99685 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785959 | 0.96 | KMT2A (0.67) | KMT2AMAPTMEN1NPSR1NPC1 | |
| SCHEMBL11841105 | 0.95 | MAPT (0.65) | KMT2AMAPTMEN1NPSR1NPC1 | |
| SCHEMBL11832841 | 0.92 | KMT2A (0.72) | KMT2AMAPTMEN1NPSR1NPC1 | |
| SCHEMBL11835233 | 0.87 | KMT2A (0.76) | KMT2AMAPTMEN1NPSR1NPC1 | |
| SCHEMBL9770215 | 0.87 | ALDH1A1 (0.65) | KMT2AMAPTMEN1ALDH1A1HTT | |
| SCHEMBL11832585 | 0.86 | MEN1 (0.68) | KMT2AMAPTMEN1RAB9AALDH1A1 | |
| SCHEMBL11766882 | 0.85 | KMT2A (0.65) | KMT2AMAPTMEN1NPSR1MAPK1 | |
| SCHEMBL11834466 | 0.85 | KMT2A (0.72) | KMT2AMAPTMEN1NPSR1NPC1 | |
| SCHEMBL6907398 | 0.84 | POLB (0.72) | KMT2AMAPTMEN1NPSR1NPC1 | |
| SCHEMBL4785961 | 0.84 | TBXA2R (0.59) | KMT2AMAPTMEN1MGLLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933814-A | ANTIPROTOZOA, ANTICOCCIDIOSIS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |