Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832669 | 0.88 | ITGB3 (0.49) | MAPTITGB3ITGA2BALDH1A1ALOX15 | |
| SCHEMBL11837846 | 0.87 | MAPT (0.47) | MAPTITGB3ITGA2BALDH1A1ALOX15 | |
| SCHEMBL11835140 | 0.86 | ITGB3 (0.62) | MAPTITGB3ITGA2BALDH1A1ALOX15 | |
| SCHEMBL11837072 | 0.86 | MAPT (0.46) | MAPTITGB3ITGA2BALDH1A1ALOX15 | |
| SCHEMBL11825953 | 0.85 | ITGB3 (0.54) | MAPTITGB3ITGA2BALDH1A1ALOX15 | |
| SCHEMBL11837853 | 0.84 | MAPT (0.46) | MAPTITGB3ITGA2BALDH1A1ALOX15 | |
| SCHEMBL11841185 | 0.84 | DRD4 (0.44) | MAPTITGB3ITGA2BALDH1A1ALOX15 | |
| SCHEMBL11831414 | 0.84 | ITGB3 (0.46) | MAPTITGB3ITGA2BALDH1A1ALOX15 | |
| SCHEMBL11841659 | 0.83 | MAPT (0.44) | MAPTITGB3ITGA2BALDH1A1ALOX15 | |
| SCHEMBL11830077 | 0.83 | ITGB3 (0.46) | MAPTITGB3ITGA2BALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956334-A | CHOLESTEROL AND TRIGLYCERIDE LOWERING ACTIVITY IN BLOOD | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-05-11 | — | — | US | disclosed |