Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444686 | 0.82 | PPARG (0.54) | PPARGPPARAALDH1A1HPGDCTBP2 | |
| SCHEMBL3433828 | 0.80 | PPARG (0.50) | PPARGPPARAHPGDKMT2AMEN1 | |
| SCHEMBL7372199 | 0.80 | PPARG (0.50) | PPARGPPARAHPGDKMT2AMEN1 | |
| SCHEMBL30963028 | 0.79 | SLC1A5 (0.53) | TAAR1SLC1A5 | |
| SCHEMBL5322254 | 0.79 | SLC1A5 (0.53) | TAAR1SLC1A5 | |
| SCHEMBL8819750 | 0.79 | SLC1A5 (0.53) | TAAR1SLC1A5 | |
| SCHEMBL8819746 | 0.79 | SLC1A5 (0.53) | TAAR1SLC1A5 | |
| SCHEMBL31688608 | 0.77 | PPARG (0.46) | PPARGPPARATAAR1ALDH1A1HPGD | |
| SCHEMBL22444604 | 0.77 | PPARG (0.46) | PPARGPPARATAAR1ALDH1A1HPGD | |
| SCHEMBL16672535 | 0.76 | TAAR1 (0.41) | PPARGPPARATAAR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |