Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372199 | 1.00 | PPARG (0.50) | PPARGPPARACNR2TSHRKEAP1 | |
| SCHEMBL11823662 | 0.89 | MMP12 (0.58) | TSHRMMEHTT | |
| SCHEMBL27884209 | 0.88 | GRIK1 (0.54) | PPARGPPARAKEAP1KMT2ANPC1 | |
| SCHEMBL19469366 | 0.88 | CNR2 (0.49) | PPARGPPARACNR2TSHRKEAP1 | |
| SCHEMBL31229953 | 0.86 | MAPT (0.52) | PPARGPPARANPC1RAB9ATDP1 | |
| SCHEMBL9753996 | 0.86 | CNR2 (0.47) | PPARGPPARACNR2TSHRKEAP1 | |
| SCHEMBL1133621 | 0.85 | MAPT (0.55) | SMN1; SMN2 | |
| SCHEMBL27413116 | 0.85 | MAPT (0.55) | SMN1; SMN2 | |
| SCHEMBL27438257 | 0.85 | MAPT (0.55) | SMN1; SMN2 | |
| SCHEMBL27540285 | 0.85 | MAPT (0.55) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2033635-A1 | Short-chain fatty acid derivatives for treating pruritus | Asan Laboratories Company (Cayman) Limited (CN) | 2009-03-11 | — | — | EP | claimed |
| EP-1951813-A1 | METHOD OF REDUCING THE STYRENE CONTENT OF A POLY (ARYLENE ETHER) POLYSTYRENE BLEND, AND ARTICLES COMPRISING THE RESULTING THERMOPLASTIC RESIN | General Electric Company (US) | 2008-08-06 | — | — | EP | claimed |
| US-20080107646-A1 | Administering phenylbutyric acid derivative and pharmaceutically acceptable carrier | Sunny Pharmtech Inc. (TW) | 2008-05-08 | — | — | US | claimed |
| US-7314909-B2 | Method of reducing the styrene content of a poly(arylene ether)/polystyrene blend, and articles comprising the resulting thermoplastic resin | GENERAL ELECTRIC COMPANY (US) | 2008-01-01 | — | — | US | claimed |
| WO-2007047217-A1 | METHOD OF REDUCING THE STYRENE CONTENT OF A POLY (ARYLENE ETHER) POLYSTYRENE BLEND, AND ARTICLES COMPRISING THE RESULTING THERMOPLASTIC RESIN | GENERAL ELECTRIC COMPANY (US) | 2007-04-26 | — | — | WO | claimed |
| US-20070083035-A1 | Method of reducing the styrene content of a poly(arylene ether)/polystyrene blend, and articles comprising the resulting thermoplastic resin | SABIC GLOBAL TECHNOLOGIES IP B.V. (NL) | 2007-04-12 | — | — | US | claimed |
| US-6403646-B1 | ADMINISTERING PHENYLBUTYRIC ACID OR DERIVATIVES TO TREAT LIVER DISEASE AND EMPHYSEMA CAUSED BY PROTEASE INHIBITOR TYPE Z MUTATION; STIMULATES SECRETION WITHOUT INCREASING SYNTHESIS OF PROTEIN | PERLMUTTER DAVID H (US) | 2002-06-11 | — | — | US | claimed |
| US-8846039-B2 | Method for ameliorating pruritus | ASAN LABORATORIES COMPANY (CAYMAN), LIMITED (TW) | 2014-09-30 | — | — | US | disclosed |
| CN-101380317-B | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV PHARMACEUTICAL CO LTD | 2010-12-08 | — | — | CN | disclosed |
| EP-1951813-B1 | METHOD OF REDUCING THE STYRENE CONTENT OF A POLY (ARYLENE ETHER) POLYSTYRENE BLEND | SABIC INNOVATIVE PLASTICS IP (NL) | 2010-12-01 | — | — | EP | disclosed |
| EP-2033635-A1 | Short-chain fatty acid derivatives for treating pruritus | Asan Laboratories Company (Cayman) Limited (CN) | 2009-03-11 | — | — | EP | disclosed |
| CN-101380317-A | Pharmaceutical composition for relieving pruritus | CAYMAN ISLAND SHANGANSHENG DEV (CN) | 2009-03-11 | — | — | CN | disclosed |
| EP-2030616-A1 | Short-chain fatty acid derivatives for treating pruritus | Asan Laboratories Company (Cayman) Limited (CN) | 2009-03-04 | — | — | EP | disclosed |
| WO-1996038528-A1 | BETAINE ESTERS FOR DELIVERY OF ALCOHOLS | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-05 | — | — | WO | disclosed |
| EP-0725635-A1 | PHENYLACETATE AND DERIVATIVES ALONE OR IN COMBINATION WITH OTHER COMPOUNDS AGAINST NEOPLASTIC CONDITIONS AND OTHER DISORDERS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995010271-A2 | PHENYLACETATE AND DERIVATIVES ALONE OR IN COMBINATION WITH OTHER COMPOUNDS AGAINST NEOPLASTIC CONDITIONS AND OTHER DISORDERS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-04-20 | — | — | WO | disclosed |
| US-4965397-A | Novel dibasic acid salts and their synthesis | ETHYL CORPORATION (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0138403-B1 | PROCESS FOR PREPARING PHOSPHINIC ACID INTERMEDIATES | E.R. Squibb & Sons, Inc. (US) | 1989-03-15 | — | — | EP | disclosed |
| US-4602092-A | Method for making phosphinic acid intermediates | E. R. SQUIBB & SONS, INC. (US) | 1986-07-22 | — | — | US | disclosed |
| EP-0138403-A2 | Process for preparing phosphinic acid intermediates | E.R. Squibb & Sons, Inc. (US) | 1985-04-24 | — | — | EP | disclosed |