Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 4/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823662 | 0.82 | MMP12 (0.58) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11828178 | 0.80 | MMP12 (0.55) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11829069 | 0.79 | MMP12 (0.61) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11827662 | 0.78 | MMP12 (0.56) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11828864 | 0.77 | MMP12 (0.47) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL1818244 | 0.77 | TSHR (0.43) | LMNATSHRHTT | |
| SCHEMBL11838769 | 0.75 | MMP12 (0.54) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL11829944 | 0.75 | MMP12 (0.52) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL425971 | 0.73 | MMP12 (0.59) | MMP12MMP2MMP9MMP13MMP14 | |
| SCHEMBL7509128 | 0.73 | HPGD (0.59) | MMP9MMP14FFAR1MMELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |