Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 9/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 9/20 | 0.48 |
| ▸ | NTRK3 | Q16288 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 3/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295367 | 0.80 | NTRK1 (0.57) | NTRK1NTRK2NTRK3SMN1; SMN2LMNA | |
| SCHEMBL11842419 | 0.76 | NTRK1 (0.52) | NTRK1NTRK2NTRK3MEN1KMT2A | |
| SCHEMBL21295423 | 0.75 | NTRK1 (0.61) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL5863266 | 0.73 | PDE7A (0.82) | PDE7AMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29780387 | 0.73 | PDE7A (0.82) | PDE7AMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL13780156 | 0.73 | NTRK1 (0.48) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL10528041 | 0.72 | EPAS1 (0.44) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL13780151 | 0.72 | NTRK1 (0.60) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL21295325 | 0.71 | NTRK1 (0.81) | NTRK1NTRK2NTRK3IGF1RFGFR1 | |
| SCHEMBL30743934 | 0.71 | NTRK1 (0.81) | NTRK1NTRK2NTRK3IGF1RFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933814-A | ANTIPROTOZOA, ANTICOCCIDIOSIS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |