Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 8/20 | 0.52 |
| ▸ | NTRK2 | Q16620 | 8/20 | 0.52 |
| ▸ | IGF1R | P08069 | 5/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.52 |
| ▸ | NTRK3 | Q16288 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11767801 | 0.85 | MAPT (0.52) | MAPTKMT2AMEN1HTTGSK3A | |
| SCHEMBL11832703 | 0.85 | HSPB1 (0.50) | MAPTKMT2AMEN1HTTHSPB1 | |
| SCHEMBL11767196 | 0.84 | GSK3B (0.41) | MAPTKMT2AMEN1HTTGSK3A | |
| SCHEMBL11831354 | 0.82 | NTRK1 (0.77) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL21295367 | 0.81 | NTRK1 (0.57) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL11838709 | 0.79 | NTRK1 (0.52) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL10527978 | 0.76 | NTRK1 (0.49) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL11830607 | 0.76 | PDE7A (0.48) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL10525747 | 0.75 | NTRK1 (0.51) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL10528157 | 0.75 | NTRK1 (0.48) | NTRK1NTRK2IGF1RFGFR1NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933814-A | ANTIPROTOZOA, ANTICOCCIDIOSIS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |