Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.82 |
| ▸ | MAPT | P10636 | 6/20 | 0.82 |
| ▸ | NPC1 | O15118 | 3/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.82 |
| ▸ | RAB9A | P51151 | 2/20 | 0.82 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.82 |
| ▸ | MYOC | Q99972 | 1/20 | 0.82 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | F13A1 | P00488 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004478 | 0.91 | MEN1 (1.00) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL9285911 | 0.91 | KMT2A (0.79) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11839306 | 0.86 | MAPT (0.62) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11838723 | 0.86 | MEN1 (0.85) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11837226 | 0.85 | MEN1 (0.78) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11837944 | 0.85 | MEN1 (0.82) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11027238 | 0.85 | MEN1 (0.88) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11832409 | 0.85 | MEN1 (0.88) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL9367406 | 0.84 | KMT2A (0.77) | MEN1KMT2AMAPTNPC1MAPK1 | |
| SCHEMBL11832321 | 0.84 | MEN1 (0.62) | MEN1KMT2AMAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933814-A | ANTIPROTOZOA, ANTICOCCIDIOSIS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |