Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.77 |
| ▸ | MEN1 | O00255 | 7/20 | 0.77 |
| ▸ | MAPT | P10636 | 6/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | MYOC | Q99972 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | F13A1 | P00488 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642700 | 0.90 | KMT2A (0.81) | KMT2AMEN1MAPTNPC1MAPK1 | |
| SCHEMBL16922176 | 0.90 | KMT2A (0.81) | KMT2AMEN1MAPTNPC1MAPK1 | |
| SCHEMBL9926973 | 0.89 | MAPT (0.74) | KMT2AMEN1MAPTNPC1MAPK1 | |
| Phosphine SCHEMBL28320532 | 0.88 | KMT2A (0.78) | KMT2AMEN1MAPTNPC1MAPK1 | |
| SCHEMBL11004478 | 0.87 | MEN1 (1.00) | KMT2AMEN1MAPTNPC1MAPK1 | |
| SCHEMBL13192698 | 0.86 | MAPT (0.69) | KMT2AMEN1MAPTNPC1MAPK1 | |
| SCHEMBL3737969 | 0.86 | MEN1 (0.73) | KMT2AMEN1MAPTNPC1MAPK1 | |
| SCHEMBL4690573 | 0.85 | MEN1 (0.79) | KMT2AMEN1MAPTNPC1MAPK1 | |
| SCHEMBL11830737 | 0.84 | MEN1 (0.82) | KMT2AMEN1MAPTNPC1MAPK1 | |
| SCHEMBL6516221 | 0.84 | KMT2A (0.73) | KMT2AMEN1MAPTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105660-B1 | PREPARATION OF BIS-(AMINOPHENYL) ETHERS FROM (N-ACETYL) AMINOPHENOLS OR THEIR PHENOLATES | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1985-11-27 | — | — | EP | claimed |
| US-4551551-A | Preparation of bis(aminophenyl) ethers from (N-acetyl)aminophenols or their phenolates | MALLINCKRODT, INC. (US) | 1985-11-05 | — | — | US | claimed |
| EP-0105660-A1 | Preparation of bis-(aminophenyl) ethers from (N-acetyl) aminophenols or their phenolates | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1984-04-18 | — | — | EP | claimed |
| WO-2025083280-A1 | SORAFENIB ANALOGS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITAT DE BARCELONA (ES) | 2025-04-24 | — | — | WO | disclosed |
| EP-0303415-B1 | Herbicidally active phenoxy-alkanecarboxylic acid derivatives | SUNTORY LTD (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-5205855-A | Postemergence, preemergence herbicides | SUNTORY LIMITED (JP) | 1993-04-27 | — | — | US | disclosed |
| US-4976773-A | SELECTIVITY BETWEEN MONOCOYLEDON PLANTS | SUNTORY LIMITED (JP) | 1990-12-11 | — | — | US | disclosed |
| EP-0303415-A2 | Herbicidally active phenoxy-alkanecarboxylic acid derivatives | SUNTORY LIMITED (JP) | 1989-02-15 | — | — | EP | disclosed |
| EP-0105660-B1 | PREPARATION OF BIS-(AMINOPHENYL) ETHERS FROM (N-ACETYL) AMINOPHENOLS OR THEIR PHENOLATES | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1985-11-27 | — | — | EP | disclosed |
| EP-0105660-A1 | Preparation of bis-(aminophenyl) ethers from (N-acetyl) aminophenols or their phenolates | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1984-04-18 | — | — | EP | disclosed |
| EP-0105660-A1 | Preparation of bis-(aminophenyl) ethers from (N-acetyl) aminophenols or their phenolates | MALLINCKRODT, INC.(a Missouri corporation) (US) | 1984-04-18 | — | — | EP | disclosed |