Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.66 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.66 |
| ▸ | PPARG | P37231 | 5/20 | 0.66 |
| ▸ | PPARD | Q03181 | 5/20 | 0.66 |
| ▸ | PPARA | Q07869 | 5/20 | 0.66 |
| ▸ | F7 | P08709 | 5/20 | 0.66 |
| ▸ | F3 | P13726 | 5/20 | 0.66 |
| ▸ | TERT | O14746 | 3/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | FABP4 | P15090 | 3/20 | 0.66 |
| ▸ | TOP1 | P11387 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleic Acid SCHEMBL11831371 | 1.00 | PPARG (0.66) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL6035118 | 0.94 | PPARG (0.74) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL28479638 | 0.94 | PPARG (0.74) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL3821 | 0.94 | PPARG (0.74) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL6035123 | 0.94 | PPARG (0.74) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL3822 | 0.94 | PPARG (0.74) | PPARGPPARDPPARAF7F3 | |
| Palmitoleic Acid SCHEMBL28647714 | 0.94 | PPARG (0.74) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL30696163 | 0.94 | PPARG (0.74) | PPARGPPARDPPARAF7F3 | |
| Erucic Acid SCHEMBL28372321 | 0.94 | PPARG (0.74) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL27963111 | 0.94 | PPARG (0.74) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992333-A | NITROGEN AND SULFUR CONTAINING COPOLYMER IS SELF-CROSSLINKING BINDER | ROHM AND HAAS COMPANY (US) | 1976-11-16 | — | — | US | disclosed |