Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 4/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11680841 | 0.86 | HTR2A (0.57) | HTR2AHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL11841997 | 0.86 | ADRA2A (0.70) | HTR2AHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL11679349 | 0.84 | MEN1 (0.60) | HTR2AHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL11841817 | 0.83 | ADRA2A (0.60) | HTR2AHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL11865326 | 0.83 | HTR2A (0.56) | HTR2AHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL11844116 | 0.83 | HTR2A (0.56) | HTR2AHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL6465788 | 0.83 | HTR2A (0.88) | HTR2AHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL11848458 | 0.83 | CDK4 (0.59) | HTR2AHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL11681652 | 0.83 | HTR2A (0.53) | HTR2AHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL11860457 | 0.82 | ADRA2A (0.59) | HTR2AHTR1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3997539-A | HYPOTENSIVE, TRANQUILIZER | AMERICAN HOECHST CORPORATION (US) | 1976-12-14 | — | — | US | claimed |
| US-3997539-A | HYPOTENSIVE, TRANQUILIZER | AMERICAN HOECHST CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |