Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836995 | 0.87 | CYP1A2 (0.49) | NPC1RAB9APOLBALDH1A1KDM4E | |
| SCHEMBL9667362 | 0.85 | POLB (0.49) | NPC1RAB9APOLBALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL17999749 | 0.83 | POLB (0.47) | NPC1RAB9APOLBALDH1A1KDM4E | |
| SCHEMBL11846007 | 0.81 | ACP1 (0.42) | F2F10PLGPLAUPLAT | |
| SCHEMBL11834166 | 0.81 | GAA (0.51) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL11845253 | 0.81 | PLAU (0.35) | POLBALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11835118 | 0.81 | NPC1 (0.47) | NPC1RAB9APOLBALDH1A1MEN1 | |
| SCHEMBL11834939 | 0.77 | RAB9A (0.39) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL11844519 | 0.77 | PLAU (0.35) | POLBALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11837380 | 0.77 | NPC1 (0.42) | NPC1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959488-A | 1-Substituted biguanides for treating hyperacidity or ulceration | WILLIAM H. RORER, INC. (US) | 1976-05-25 | — | — | US | disclosed |