Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 6/20 | 0.42 |
| ▸ | PRKCB | P05771 | 6/20 | 0.42 |
| ▸ | PRKCA | P17252 | 6/20 | 0.42 |
| ▸ | GSK3B | P49841 | 6/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11838059 | 0.86 | KDM4E (0.47) | KDM4EHSD17B10TSHRPRKCGPRKCB | |
| SCHEMBL11842021 | 0.85 | MAPT (0.57) | KDM4EHSD17B10TSHRPRKCGPRKCB | |
| SCHEMBL11834589 | 0.84 | KDM4E (0.63) | KDM4EHSD17B10TSHRPRKCGPRKCB | |
| Hydrochloric Acid SCHEMBL11837384 | 0.84 | MAPT (0.56) | KDM4EHSD17B10TSHRPRKCGPRKCB | |
| Hydrochloric Acid SCHEMBL11833093 | 0.83 | KDM4E (0.61) | KDM4EHSD17B10TSHRPRKCGPRKCB | |
| SCHEMBL11669099 | 0.82 | KDM4E (0.52) | KDM4EHSD17B10TSHRPRKCGPRKCB | |
| Oxalic Acid SCHEMBL11834754 | 0.81 | KDM4E (0.51) | KDM4EHSD17B10TSHRPRKCGPRKCB | |
| SCHEMBL9303541 | 0.81 | CYP2D6 (0.47) | KDM4EHSD17B10TSHRPRKCGPRKCB | |
| SCHEMBL9303584 | 0.80 | CYP2D6 (0.57) | KDM4EHSD17B10TSHRPRKCGPRKCB | |
| Hydrochloric Acid SCHEMBL8135773 | 0.79 | CYP2D6 (0.56) | KDM4EHSD17B10TSHRPRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |