Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 2/20 | 0.42 |
| ▸ | PRKCB | P05771 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11838059 | 0.94 | KDM4E (0.47) | KDM4EHSD17B10TSHRMAPTCSF1R | |
| SCHEMBL11834527 | 0.87 | KDM4E (0.43) | KDM4EHSD17B10TSHRMAPTCSF1R | |
| Hydrochloric Acid SCHEMBL11843968 | 0.86 | KDM4E (0.42) | KDM4EHSD17B10TSHRMAPTCSF1R | |
| SCHEMBL11669099 | 0.85 | KDM4E (0.52) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| SCHEMBL11835521 | 0.83 | HSD17B10 (0.45) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11835498 | 0.82 | HSD17B10 (0.44) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| SCHEMBL11842021 | 0.81 | MAPT (0.57) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| SCHEMBL11834719 | 0.81 | KDM4E (0.46) | KDM4EHSD17B10TSHRMAPTCSF1R | |
| SCHEMBL11835817 | 0.81 | KDM4E (0.61) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| SCHEMBL11834589 | 0.81 | KDM4E (0.63) | KDM4EHSD17B10TSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | disclosed |