Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836987 | 0.82 | TRPV1 (0.47) | MAPKAPK2MAPTLMNAHTTHTR6 | |
| SCHEMBL11842839 | 0.82 | MAPKAPK2 (0.57) | MAPKAPK2HSD17B10CYP1A2LMNAHTR6 | |
| SCHEMBL11844570 | 0.81 | SIRT2 (0.43) | HPGDKDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL11841342 | 0.78 | SIRT1 (0.47) | MAPKAPK2HPGDKDM4EALDH1A1CYP2C9 | |
| SCHEMBL11830715 | 0.76 | PTGS1 (0.40) | HTR6 | |
| SCHEMBL11838762 | 0.76 | MAPKAPK2 (0.42) | MAPKAPK2HPGDKDM4ECYP2C9MAPT | |
| SCHEMBL11840446 | 0.76 | MAPKAPK2 (0.42) | MAPKAPK2HPGDKDM4EALDH1A1CYP2C9 | |
| SCHEMBL11847982 | 0.76 | MAPKAPK2 (0.42) | MAPKAPK2CYP2C9MAPTLMNAHTT | |
| SCHEMBL11829601 | 0.76 | MCHR1 (0.43) | MAPKAPK2CYP2C9MAPTHTTS1PR1 | |
| SCHEMBL11833958 | 0.76 | MAPKAPK2 (0.40) | MAPKAPK2CYP2C9MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948939-A | 9-Acyl-1,2,3,4-tetrahydrocarbazole-3 and 4-carboxylic acids | STERLING DRUG INC. (US) | 1976-04-06 | — | — | US | disclosed |