Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 4/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834747 | 0.78 | CTSV (0.41) | CTSVCTSLPDPK1MEN1KMT2A | |
| SCHEMBL3836372 | 0.75 | KDM4E (0.50) | CTSVCTSLPDPK1MEN1KMT2A | |
| SCHEMBL11835107 | 0.75 | KDM4E (0.58) | CTSVCTSLPDPK1MEN1KMT2A | |
| SCHEMBL27575117 | 0.72 | NOTUM (0.48) | CTSVCTSLPDPK1MEN1KMT2A | |
| SCHEMBL12427052 | 0.70 | KDM4E (0.53) | MEN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL8592254 | 0.69 | PDPK1 (0.42) | CTSVCTSLPDPK1MEN1KMT2A | |
| SCHEMBL11840121 | 0.68 | PNP (0.41) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL1550048 | 0.68 | CTSV (0.59) | CTSVCTSLMEN1KMT2AMAPT | |
| SCHEMBL3032558 | 0.65 | KDM4E (0.80) | CTSVCTSLMEN1KMT2AMAPT | |
| SCHEMBL5907130 | 0.64 | CTSV (0.51) | CTSVCTSLPDPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948903-A | Substituted N-(1,2-dihydro-2-oxonicotinyl)-cephalexins and -cephaloglycins | PARKE, DAVIS & COMPANY (US) | 1976-04-06 | — | — | US | disclosed |