Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11833164 | 0.99 | KDM4E (0.47) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11836348 | 0.86 | KDM4E (0.65) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11835514 | 0.86 | KDM4E (0.50) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11834520 | 0.86 | KMT2A (0.46) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11837486 | 0.85 | KMT2A (0.58) | KDM4EKMT2AMEN1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL11828807 | 0.85 | KDM4E (0.64) | KDM4EKMT2AMEN1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL11835491 | 0.85 | KDM4E (0.49) | KDM4EKMT2AMEN1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL11843962 | 0.85 | KMT2A (0.45) | KDM4EKMT2AMEN1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL11835272 | 0.84 | KMT2A (0.57) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11838053 | 0.80 | KDM4E (0.51) | KDM4EKMT2AMEN1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |