Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 2/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11828807 | 0.99 | KDM4E (0.64) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11834830 | 0.86 | KDM4E (0.48) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11835472 | 0.86 | KDM4E (0.62) | KDM4EKMT2AMEN1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL11833164 | 0.85 | KDM4E (0.47) | KDM4EKMT2AMEN1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL11846087 | 0.85 | KDM4E (0.61) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11837486 | 0.84 | KMT2A (0.58) | KDM4EKMT2AMEN1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL11835272 | 0.83 | KMT2A (0.57) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11842018 | 0.81 | KDM4E (0.69) | KDM4EKMT2AMEN1TSHRMAPT | |
| SCHEMBL11832922 | 0.80 | KDM4E (0.72) | KDM4EKMT2AMEN1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL11837379 | 0.80 | KDM4E (0.67) | KDM4EKMT2AMEN1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |