SCHEMBL11834868

SCHEMBL11834868

Cc1cc(C)c(Nc2ccc(O)c3ccccc23)c(C)c1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 7/20 0.53
IDO1 P14902 6/20 0.53
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
MAP1LC3B Q9GZQ8 1/20 0.52
GAA P10253 2/20 0.49
G6PD P11413 1/20 0.49
EP300 Q09472 2/20 0.47
KAT2B Q92831 2/20 0.47
KAT8 Q9H7Z6 2/20 0.47
CDC25B P30305 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8931188 0.78 IDO1 (0.68) IDO1EP300KAT2BKAT8CDC25B
SCHEMBL11840391 0.77 IDO1 (0.58) IDO1MEN1KMT2AMAP1LC3BGAA
SCHEMBL20483185 0.77 RAPGEF4 (0.58) RAPGEF4
SCHEMBL18351203 0.76 RAPGEF4 (0.61) RAPGEF4MEN1KMT2AGAACDC25B
SCHEMBL2199650 0.76 RAPGEF4 (0.70) RAPGEF4
SCHEMBL28194328 0.75 CYP1A2 (0.53) RAPGEF4IDO1MEN1KMT2A
SCHEMBL13140103 0.74 RAPGEF4 (0.63) RAPGEF4MEN1KMT2A
SCHEMBL25287525 0.74 MEN1 (0.71) MEN1KMT2AMAP1LC3BGAAG6PD
SCHEMBL25791942 0.74 MEN1 (0.47) IDO1MEN1KMT2AMAP1LC3BGAA
SCHEMBL21165036 0.74 RAPGEF4 (0.47) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 US disclosed
US-3947471-A CHROMOGENIC SUMITOMO CHEMICAL COMPANY, LTD. (JA) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 RAPGEF4 3390/4885IDO1 3157/4885MEN1 3357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.