Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.71 |
| ▸ | PTGER3 | P43115 | 14/20 | 0.71 |
| ▸ | PTGER2 | P43116 | 10/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4377087 | 0.93 | PTGER4 (0.62) | PTGER4PTGER3PTGER2KCNH2 | |
| SCHEMBL4377089 | 0.93 | PTGER4 (0.62) | PTGER4PTGER3PTGER2KCNH2 | |
| SCHEMBL4377090 | 0.93 | PTGER4 (0.62) | PTGER4PTGER3PTGER2KCNH2 | |
| SCHEMBL4377952 | 0.93 | PTGER4 (0.62) | PTGER4PTGER3PTGER2KCNH2 | |
| SCHEMBL5762456 | 0.92 | PTGER4 (0.61) | PTGER4PTGER3PTGER2KCNH2 | |
| SCHEMBL6803068 | 0.91 | PTGER4 (0.60) | PTGER4PTGER3PTGER2KCNH2 | |
| SCHEMBL6803076 | 0.91 | PTGER4 (0.60) | PTGER4PTGER3PTGER2KCNH2 | |
| SCHEMBL7245447 | 0.88 | PTGER4 (0.72) | PTGER4PTGER3PTGER2 | |
| SCHEMBL7245443 | 0.88 | PTGER4 (0.72) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5250941 | 0.87 | PTGER4 (0.56) | PTGER4PTGER3PTGER2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975399-A | PROSTAGLANDIN LIKE ACTIVITY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-17 | — | — | US | claimed |