Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835660 | 1.00 | BLM (0.46) | BLMACHEBACE1LMNAPPARA | |
| SCHEMBL3626405 | 0.87 | BLM (0.50) | BLMACHEBACE1LMNAPTPN1 | |
| SCHEMBL3626403 | 0.87 | BLM (0.50) | BLMACHEBACE1LMNAPTPN1 | |
| SCHEMBL10768922 | 0.85 | ALDH1A1 (0.50) | BLMLMNAPPARAPTPN1CYP3A4 | |
| SCHEMBL15609240 | 0.83 | ALDH1A1 (0.39) | ACHEBACE1LMNAPPARACYP3A4 | |
| SCHEMBL15609241 | 0.83 | ALDH1A1 (0.39) | ACHEBACE1LMNAPPARACYP3A4 | |
| SCHEMBL7544647 | 0.82 | ALDH1A1 (0.39) | BLMLMNAPPARAPTPN1CYP3A4 | |
| SCHEMBL7544646 | 0.82 | ALDH1A1 (0.39) | BLMLMNAPPARAPTPN1CYP3A4 | |
| SCHEMBL10548139 | 0.80 | BLM (0.46) | BLMLMNAPTPN1CYP3A4ALDH1A1 | |
| SCHEMBL2502158 | 0.80 | BLM (0.46) | BLMLMNAPTPN1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966780-A | PESTICIDES, INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1976-06-29 | — | — | US | disclosed |