Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5412777 | 0.89 | KMT2A (0.48) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL11835817 | 0.82 | KDM4E (0.61) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL11834058 | 0.81 | HSD17B10 (0.69) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL11845306 | 0.81 | KDM4E (0.49) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL11834527 | 0.81 | KDM4E (0.43) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL15631874 | 0.80 | MAPT (0.77) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11843968 | 0.80 | KDM4E (0.42) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL11843862 | 0.79 | KDM4E (0.47) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL11838059 | 0.79 | KDM4E (0.47) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11837485 | 0.79 | CACNB4 (0.43) | MAPTHSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | disclosed |