Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11843968 | 0.99 | KDM4E (0.42) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| SCHEMBL11838059 | 0.92 | KDM4E (0.47) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| SCHEMBL11834839 | 0.87 | POLB (0.43) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| Oxalic Acid SCHEMBL11834754 | 0.87 | KDM4E (0.51) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11833169 | 0.86 | PKM (0.42) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| SCHEMBL11835478 | 0.86 | MAPT (0.59) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| SCHEMBL11836098 | 0.85 | KDM4E (0.58) | KDM4EHSD17B10TSHRALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL11846094 | 0.85 | MAPT (0.58) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| SCHEMBL5412777 | 0.84 | KMT2A (0.48) | KDM4EHSD17B10TSHRMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11837410 | 0.83 | KDM4E (0.57) | KDM4EHSD17B10TSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |