Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11840637 | 1.00 | LMNA (0.36) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL11849382 | 0.78 | LMNA (0.34) | LMNAPTPN1 | |
| SCHEMBL11849388 | 0.78 | LMNA (0.34) | LMNAPTPN1 | |
| SCHEMBL11832855 | 0.77 | CYP3A4 (0.46) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL11832909 | 0.77 | CYP3A4 (0.46) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL21339941 | 0.74 | LMNA (0.48) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL14571178 | 0.73 | TDP1 (0.46) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL2004794 | 0.72 | LMNA (0.55) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL11850228 | 0.72 | PTPN1 (0.46) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL11850219 | 0.72 | PTPN1 (0.46) | LMNAMEN1CYP3A4ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966780-A | PESTICIDES, INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1976-06-29 | — | — | US | disclosed |