Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12459415 | 0.78 | GPR84 (0.54) | GPR84MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL13068848 | 0.77 | GPR84 (0.49) | GPR84MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL11852469 | 0.77 | KMT2A (0.46) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL7838080 | 0.74 | GPR84 (0.61) | GPR84MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL6648031 | 0.74 | CES1 (0.50) | MAPTALDH1A1LMNAHTTCES1 | |
| SCHEMBL11852780 | 0.73 | GPR84 (0.47) | GPR84MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL12215469 | 0.72 | GPR84 (0.42) | GPR84MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL826206 | 0.71 | — | — | |
| SCHEMBL2604394 | 0.71 | TTR (0.56) | GPR84MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL11112161 | 0.71 | BCHE (0.49) | LMNACES1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985730-A | 5-Alkyl-10-(aminocarbonyl/aminomethyl/cyano)-10,11-dihydro-5H-dibenz[b,f]azepine-10-alkanamines | G. D. SEARLE & CO. (US) | 1976-10-12 | — | — | US | disclosed |