Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846584 | 0.84 | IDO1 (0.43) | CYP19A1CYP11B1CYP11B2IDO1CYP3A4 | |
| SCHEMBL27747227 | 0.80 | IDO1 (0.53) | CYP19A1CYP11B1CYP11B2IDO1CYP3A4 | |
| SCHEMBL11569176 | 0.77 | IDO1 (0.44) | CYP19A1CYP11B1CYP11B2IDO1CYP3A4 | |
| SCHEMBL2666052 | 0.74 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2IDO1CYP3A4 | |
| SCHEMBL7970075 | 0.74 | IDO1 (0.66) | CYP19A1CYP11B1CYP11B2IDO1CYP3A4 | |
| SCHEMBL11705217 | 0.74 | IDO1 (0.66) | CYP19A1CYP11B1CYP11B2IDO1CYP3A4 | |
| SCHEMBL19732141 | 0.74 | IDO1 (0.42) | CYP19A1CYP11B1CYP11B2IDO1CYP3A4 | |
| SCHEMBL29085389 | 0.74 | IDO1 (0.45) | CYP19A1CYP11B1CYP11B2IDO1CYP3A4 | |
| SCHEMBL4225003 | 0.74 | CYP19A1 (0.39) | CYP19A1CYP11B1CYP11B2IDO1CYP3A4 | |
| SCHEMBL1885632 | 0.74 | CYP3A4 (0.46) | CYP19A1CYP11B1CYP11B2IDO1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3995050-A | PSYCHOSTIMULANTS | PARCOR (FR) | 1976-11-30 | — | — | US | disclosed |