Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9883217 | 0.84 | ROCK2 (0.90) | ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL113084 | 0.83 | ROCK2 (0.88) | ROCK2ROCK1 | |
| SCHEMBL23927641 | 0.82 | ROCK2 (0.67) | ROCK2ROCK1 | |
| SCHEMBL19886421 | 0.81 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL19886629 | 0.80 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL13074766 | 0.79 | ROCK2 (0.82) | ROCK2ROCK1 | |
| SCHEMBL22002216 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL19886626 | 0.78 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL19886628 | 0.78 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL169303 | 0.78 | ROCK2 (0.57) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424857-A1 | DUAL-ACTION INHIBITORS AND METHODS OF USING SAME | Aerie Pharmaceuticals, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |