Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27852978 | 0.88 | GABRA1 (0.60) | GABRA1GABRB2SLC6A2HTR2CGABRG2 | |
| SCHEMBL31204330 | 0.88 | GABRA1 (0.60) | GABRA1GABRB2SLC6A2HTR2CGABRG2 | |
| SCHEMBL66162 | 0.85 | GABRA1 (0.63) | GABRA1GABRB2SLC6A2HTR2CGABRG2 | |
| SCHEMBL29429205 | 0.85 | GABRA1 (0.63) | GABRA1GABRB2SLC6A2HTR2CGABRG2 | |
| Aziridine SCHEMBL11845319 | 0.82 | SLC6A2 (0.46) | GABRA1GABRB2SLC6A2HTR2CGABRG2 | |
| Ammonia Solution, Strong SCHEMBL7550582 | 0.82 | GABRA1 (0.60) | GABRA1GABRB2SLC6A2HTR2CGABRG2 | |
| Water SCHEMBL10586204 | 0.82 | GABRA1 (0.60) | GABRA1GABRB2SLC6A2HTR2CGABRG2 | |
| SCHEMBL6203906 | 0.82 | GABRA1 (0.60) | GABRA1GABRB2SLC6A2HTR2CGABRG2 | |
| Water SCHEMBL10586200 | 0.82 | GABRA1 (0.60) | GABRA1GABRB2SLC6A2HTR2CGABRG2 | |
| Water SCHEMBL2581333 | 0.82 | GABRA1 (0.60) | GABRA1GABRB2SLC6A2HTR2CGABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3977923-A | Method and solid propellant with unsaturated aziridine cured binder | THE GENERAL TIRE & RUBBER COMPANY (US) | 1976-08-31 | — | — | US | disclosed |