Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000934 | 0.98 | ZDHHC7 (0.47) | ZDHHC7ESR1ESR2FAAHHTR7 | |
| SCHEMBL11857063 | 0.98 | ZDHHC7 (0.47) | ZDHHC7ESR1ESR2FAAHHTR7 | |
| SCHEMBL11859008 | 0.98 | ZDHHC7 (0.47) | ZDHHC7ESR1ESR2FAAHHTR7 | |
| SCHEMBL11855985 | 0.95 | ESR1 (0.45) | ZDHHC7ESR1ESR2FAAHHTR7 | |
| SCHEMBL11861833 | 0.89 | ESR1 (0.47) | ESR1ESR2FAAHGAAHPGD | |
| SCHEMBL2044614 | 0.86 | ESR1 (0.45) | ESR1ESR2GAAALDH1A1HDAC3 | |
| SCHEMBL11852675 | 0.85 | L3MBTL1 (0.55) | ZDHHC7ESR1ESR2HPGDALDH1A1 | |
| SCHEMBL8659505 | 0.84 | ZDHHC7 (0.47) | ZDHHC7ESR1ESR2HPGDALDH1A1 | |
| SCHEMBL11847688 | 0.84 | L3MBTL1 (0.53) | ZDHHC7ESR1ESR2HPGDALDH1A1 | |
| SCHEMBL3264863 | 0.84 | ESR1 (0.50) | ESR1ESR2HTR7GAAMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991201-A | 1-(β-Aryl-β-R-ethyl)imidazoles as antimicrobial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-09 | — | — | US | disclosed |