Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11801484 | 0.70 | ADORA2A (0.43) | MAPTALDH1A1KMT2AL3MBTL1HTT | |
| SCHEMBL14321735 | 0.69 | TSHR (0.53) | ALDH1A1KMT2ARAB9ALMNAPKM | |
| SCHEMBL6445692 | 0.69 | ACE2 (0.39) | MAPTALDH1A1RAB9AMAPK1PKM | |
| SCHEMBL31402496 | 0.68 | MAPT (0.51) | MAPTALDH1A1KMT2AL3MBTL1APAF1 | |
| SCHEMBL526407 | 0.68 | TSHR (0.48) | MAPTALDH1A1KMT2AL3MBTL1RAB9A | |
| SCHEMBL10948733 | 0.68 | TSHR (0.49) | MAPTALDH1A1KMT2AL3MBTL1LMNA | |
| SCHEMBL4054817 | 0.67 | MAPT (0.59) | MAPTALDH1A1KMT2AL3MBTL1APAF1 | |
| SCHEMBL8603134 | 0.67 | ACE2 (0.40) | ALDH1A1RAB9APKMKDM4ENPSR1 | |
| SCHEMBL6003260 | 0.67 | MAPT (0.57) | MAPTALDH1A1KMT2AL3MBTL1APAF1 | |
| SCHEMBL21840823 | 0.66 | TDP2 (0.39) | MAPTALDH1A1KMT2APKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939276-A | ANTHRAQUINONES, ASTHMA, ANTIALLERGENS | BURROUGHS WELLCOME CO. (US) | 1976-02-17 | — | — | US | disclosed |