Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 12/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11847294 | 0.97 | OPRL1 (0.46) | OPRL1OPRM1OPRD1OPRK1CHRM4 | |
| SCHEMBL11855275 | 0.95 | OPRL1 (0.48) | OPRL1OPRM1OPRD1OPRK1CHRM4 | |
| SCHEMBL11846166 | 0.91 | OPRL1 (0.49) | OPRL1OPRM1OPRD1OPRK1CHRM4 | |
| SCHEMBL11846479 | 0.90 | OPRL1 (0.47) | OPRL1OPRM1OPRD1OPRK1CHRM4 | |
| SCHEMBL11847236 | 0.89 | CHRM4 (0.48) | OPRL1OPRM1OPRD1OPRK1CHRM4 | |
| SCHEMBL11848056 | 0.88 | OPRM1 (0.51) | OPRL1OPRM1OPRD1OPRK1CHRM4 | |
| SCHEMBL11852984 | 0.87 | OPRM1 (0.48) | OPRL1OPRM1OPRD1OPRK1CHRM4 | |
| SCHEMBL11850054 | 0.86 | OPRL1 (0.49) | OPRL1OPRM1OPRD1OPRK1CHRM4 | |
| SCHEMBL11849718 | 0.86 | OPRL1 (0.49) | OPRL1OPRM1OPRD1OPRK1CHRM4 | |
| SCHEMBL11845218 | 0.86 | OPRL1 (0.47) | OPRL1OPRM1OPRD1OPRK1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3979390-A | Butyrophenone derivatives and production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-09-07 | — | — | US | disclosed |