Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11849390 | 1.00 | PARP1 (0.46) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL15468255 | 0.82 | HPGD (0.42) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL11787750 | 0.79 | PARP1 (0.52) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL11787753 | 0.79 | PARP1 (0.52) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL713860 | 0.77 | KDM1A (0.42) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL23252520 | 0.76 | PARP1 (0.48) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL20161973 | 0.76 | PARP1 (0.48) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL25599133 | 0.74 | PARP1 (0.47) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL30451881 | 0.73 | PARP1 (0.50) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL28539262 | 0.73 | PARP1 (0.50) | PARP1HDAC8HDAC6ACHESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3988332-A | Hydrocarbylidene compounds of niobium and tantalum | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-10-26 | — | — | US | disclosed |