Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551195 | 0.84 | KDM1A (0.41) | KDM1ACES2CES1DEGS1ALDH1A1 | |
| SCHEMBL9814341 | 0.84 | KDM1A (0.41) | KDM1ACES2CES1DEGS1ALDH1A1 | |
| SCHEMBL28792582 | 0.84 | KDM1A (0.41) | KDM1ACES2CES1DEGS1ALDH1A1 | |
| SCHEMBL3442786 | 0.80 | KDM1A (0.39) | KDM1ACES2CES1DEGS1ALDH1A1 | |
| SCHEMBL4503311 | 0.80 | TSHR (0.50) | ALDH1A1TSHRTDP1NR4A1NR4A2 | |
| SCHEMBL3442788 | 0.80 | KDM1A (0.39) | KDM1ACES2CES1DEGS1ALDH1A1 | |
| SCHEMBL4503310 | 0.80 | TSHR (0.50) | ALDH1A1TSHRTDP1NR4A1NR4A2 | |
| SCHEMBL4503313 | 0.80 | TSHR (0.50) | ALDH1A1TSHRTDP1NR4A1NR4A2 | |
| SCHEMBL10604768 | 0.79 | CES1 (0.41) | KDM1ACES2CES1DEGS1ALDH1A1 | |
| SCHEMBL17616707 | 0.79 | CES1 (0.41) | KDM1ACES2CES1DEGS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3995493-B1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | TOKUYAMA CORP (JP) | 2024-07-03 | — | — | EP | disclosed |
| CN-114051497-B | Chromene compounds and photochromic optical articles | 株式会社德山 | 2024-06-28 | — | — | CN | disclosed |
| CN-118159576-A | Copolymer emulsion, and one-part thermosetting resin composition, two-part thermosetting resin composition, paint, resin cured film, and coating film using the copolymer emulsion | 株式会社力森诺科 | 2024-06-07 | — | — | CN | disclosed |
| CN-113543753-B | Method for absorbing or discharging moisture in ophthalmic medical device and ophthalmic medical device | 国立大学法人东北大学 | 2024-04-19 | — | — | CN | disclosed |
| EP-3936091-B1 | METHOD FOR ABSORBING OR DISCHARGING WATER IN OPHTHALMIC MEDICAL DEVICE AND OPHTHALMIC MEDICAL DEVICE | UNIV TOHOKU (JP) | 2023-07-19 | — | — | EP | disclosed |
| WO-2023085154-A1 | COPOLYMER EMULSION, AND ONE-PACK TYPE THERMOSETTING RESIN COMPOSITION, TWO-PACK TYPE THERMOSETTING RESIN COMPOSITION, COATING MATERIAL, RESIN CURED FILM AND COATING FILM EACH USING SAID COPOLYMER EMULSION | 株式会社レゾナック | 2023-05-19 | — | — | WO | disclosed |
| EP-2657304-B1 | AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS | MENICON CO LTD (JP) | 2022-12-07 | — | — | EP | disclosed |
| US-20220213050-A1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | TOKUYAMA CORPORATION (JP) | 2022-07-07 | — | — | US | disclosed |
| EP-3995493-A1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | Tokuyama Corporation (JP) | 2022-05-11 | — | — | EP | disclosed |
| US-20220117724-A1 | METHOD OF ABSORBING OR DISCHARGING WATER OF OPHTHALMIC MEDICAL DEVICE AND OPHTHALMIC MEDICAL DEVICE | TOHOKU UNIVERSITY (JP) | 2022-04-21 | — | — | US | disclosed |
| EP-0578087-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-4629762-A | ADVANCED EPOXIDES; MECHANICAL PROPERTIES | THE DOW CHEMICAL COMPANY (US) | 1986-12-16 | — | — | US | disclosed |
| US-4629763-A | REACTING A MIXTURE OF A COPOLYMERIZED ALKENYLPHENOL ADDITION POLYMER AND A POLYPHENOL WITH A CYANOGEN HALIDE | THE DOW CHEMICAL COMPANY (US) | 1986-12-16 | — | — | US | disclosed |
| US-4629764-A | EPOXIDES COMPRISING GLYCIDOL, POLYPHENOL AND COPOLYMERIZED ALKENYL PHENO ADDITION POLYMER; HIGH STRENGTH | THE DOW CHEMICAL COMPANY (US) | 1986-12-16 | — | — | US | disclosed |
| US-4611022-A | A MIXTURE OF A POLYPHENOL COMPOUND AND A POLYMER OF AN ALKENYL PHENOL AND UNSATURATED MONOMER; POLYEPOXIDES AND-CYANURATES | THE DOW CHEMICAL COMPANY (US) | 1986-09-09 | — | — | US | disclosed |
| US-4559399-A | CURABLE MIXTURE OF ALKENYLPHENYL CYANATE, AROMATIC POLYCYANATE ANDUNSATURATED COMPOUND; HIGH STRENGH POLYTRIAZINES | THE DOW CHEMICAL COMPANY (US) | 1985-12-17 | — | — | US | disclosed |
| US-4546131-A | COPOLYMERS OF ETHYLENICALLY UNSATURATED COMPOUNDS AND ALKENYLPHENYL CYANATE | THE DOW CHEMICAL COMPANY (US) | 1985-10-08 | — | — | US | disclosed |
| US-4277637-A | TREATMENT WITH SULFONIC ACID ION EXCHANGE RESIN | THE DOW CHEMICAL COMPANY (US) | 1981-07-07 | — | — | US | disclosed |
| US-4068676-A | RELEASE AGENTS | HALLIBURTON COMPANY (US) | 1978-01-17 | — | — | US | disclosed |
| US-3912700-A | Para-t-butyl-{60 -methylstyrene polymers | CHEVRON RES | 1975-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213050-A1 | CHROMENE COMPOUND AND PHOTOCHROMIC OPTICAL ARTICLE | CRY1, CRY2, TRIP13 | KDM1A 2323/4885CES2 2001/4885CES1 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.