Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846697 | 0.90 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11852470 | 0.85 | ALDH1A1 (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11841938 | 0.84 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11850829 | 0.84 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11849260 | 0.81 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11868895 | 0.78 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11851226 | 0.77 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11853063 | 0.77 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11850347 | 0.77 | ALDH1A1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11851610 | 0.77 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3993633-A | 2(1(2H)-phthalazinone)sulfenamides vulcanization inhibitors | MONSANTO COMPANY (US) | 1976-11-23 | — | — | US | disclosed |