Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.60 |
| ▸ | PGR | P06401 | 7/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.60 |
| ▸ | AR | P10275 | 2/20 | 0.60 |
| ▸ | TNF | P01375 | 1/20 | 0.60 |
| ▸ | IL6 | P05231 | 1/20 | 0.60 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.60 |
| ▸ | GLUL | P15104 | 1/20 | 0.60 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.60 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11852002 | 1.00 | NR3C1 (0.60) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL11686698 | 0.90 | NR3C1 (0.58) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL11686707 | 0.90 | NR3C1 (0.58) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| Prednylidene SCHEMBL1650347 | 0.89 | NR3C1 (0.70) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| Prednylidene SCHEMBL7568 | 0.89 | NR3C1 (0.70) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| Prednylidene SCHEMBL3291132 | 0.89 | NR3C1 (0.70) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| Prednylidene SCHEMBL19327135 | 0.89 | NR3C1 (0.70) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL11691134 | 0.89 | NR3C1 (0.58) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL11691125 | 0.89 | NR3C1 (0.58) | NR3C1PGRHIF1AHSD17B10ABCB11 | |
| SCHEMBL11846698 | 0.89 | NR3C1 (0.61) | NR3C1PGRHIF1AHSD17B10ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984544-A | Retinoic acid esters of steroids of the pregnane series, their use in the treatment of acne and pharmaceutical formulations useful therefor | SCHERING CORPORATION (US) | 1976-10-05 | — | — | US | disclosed |