Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 3/20 | 0.47 |
| ▸ | TRPM5 | Q9NZQ8 | 3/20 | 0.47 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 7/20 | 0.36 |
| ▸ | HTR2C | P28335 | 7/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679676 | 0.84 | PRCP (0.45) | TRPM4TRPM5GID4HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL11852646 | 0.83 | PRCP (0.44) | TRPM4TRPM5GID4HTR2AHTR2C | |
| SCHEMBL10153626 | 0.72 | MAP4K1 (0.44) | HTR2AHTR2CHTR2B | |
| SCHEMBL11646760 | 0.69 | TRPM4 (0.41) | TRPM4TRPM5 | |
| SCHEMBL11644360 | 0.69 | TRPM4 (0.41) | TRPM4TRPM5 | |
| Hydrochloric Acid SCHEMBL20912488 | 0.68 | GID4 (0.51) | TRPM4TRPM5GID4HTR2AHTR2C | |
| SCHEMBL28038489 | 0.67 | HTR2A (0.43) | HTR2AHTR2CHTR2B | |
| SCHEMBL23274901 | 0.67 | PRCP (0.69) | GID4PRCP | |
| SCHEMBL29924153 | 0.67 | PRCP (0.69) | GID4PRCP | |
| SCHEMBL763552 | 0.67 | HTR2A (0.77) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984545-A | 3,4-DIHYDROXY-PHENYL-1-ANALINE WITH BENZODIAZEPINES | THE UPJOHN COMPANY (US) | 1976-10-05 | — | — | US | disclosed |
| US-3945875-A | UNSATURATED ISOCYANATES, ADHESIVES, PEROXIDE CURING AGENT | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-03-23 | — | — | US | disclosed |