Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 15/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11851804 | 0.88 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3GABRPGABRD | |
| SCHEMBL11839087 | 0.86 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3PDE10A | |
| SCHEMBL11852666 | 0.81 | HTR2A (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26382002 | 0.77 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3GABRPGABRD | |
| SCHEMBL3627890 | 0.76 | TSHR (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL11848212 | 0.75 | TSHR (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5552108 | 0.75 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11841642 | 0.71 | EGFR (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11841635 | 0.71 | EGFR (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29739420 | 0.71 | ALDH1A1 (0.36) | SLC6A2SLC6A4SLC6A3GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998955-A | 2-CARBOXY OR 2-ALKOXYCARBONYL-PYRIDINES | CIBA-GEIGY CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |