Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.55 |
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13966066 | 1.00 | HTT (0.65) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL11853161 | 1.00 | HTT (0.65) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL12650330 | 0.85 | LMNA (0.62) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL11848186 | 0.83 | LMNA (0.48) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL11848191 | 0.83 | LMNA (0.48) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL21301921 | 0.82 | MAPT (0.49) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL8358595 | 0.81 | HTT (0.57) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL8358598 | 0.81 | HTT (0.57) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL9135442 | 0.81 | MAPT (0.56) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL9135445 | 0.81 | MAPT (0.56) | HTTLMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975379-A | METHINE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | disclosed |