SCHEMBL118541

SCHEMBL118541

Cc1cnc(N)c(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122355 0.76
SCHEMBL30017969 0.75
SCHEMBL30838764 0.75
SCHEMBL27957344 0.75 PLAU (0.47)
SCHEMBL153364 0.75
SCHEMBL172774 0.75
SCHEMBL2111945 0.75
SCHEMBL31619921 0.75
SCHEMBL120637 0.75
SCHEMBL91450 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132129-A1 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES FOR TREATING CANCER GENESIS THERAPEUTICS INC (US) 2026-05-14 US disclosed
EP-4602043-A1 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES FOR TREATING CANCER Genesis Therapeutics, Inc. (US) 2025-08-20 EP disclosed
EP-4417202-A1 ANTI-CANCER ACTION OF BAG1-SELECTIVE IMIDAZOPYRIDINE COMPOUNDS IN STEROID HORMONE RECEPTOR-POSITIVE BREAST AND PROSTATE CANCER Karlsruher Institut für Technologie (DE) 2024-08-21 EP disclosed
EP-4417203-A1 SELECTIVE ANTI-CANCER ACTION OF DISTINCT IMIDAZOPYRIDINE COMPOUNDS IN STEROID HORMONE RECEPTOR-POSITIVE BREAST, PROSTATE, AND ENDOMETIRAL CANCER Karlsruher Institut für Technologie (DE) 2024-08-21 EP disclosed
WO-2024081889-A1 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES FOR TREATING CANCER GENESIS THERAPEUTICS, INC. (US) 2024-04-18 WO disclosed
CN-117396475-A Antibacterial compounds 爱尔兰詹森科学公司 2024-01-12 CN disclosed
US-11746091-B2 Cannabinoid receptor modulators ARENA PHARMACEUTICALS, INC. (US) 2023-09-05 US disclosed
US-20230033510-A1 Compounds and Methods for Treatment of Visceral Pain ARENA PHARMACEUTICALS, INC. 2023-02-02 US disclosed
US-11345702-B1 PGDH inhibitors and methods of making and using MYOFORTE THERAPEUTICS, INC. (US) 2022-05-31 US disclosed
EP-3268373-B1 TRICYCLIC DLK INHIBITORS AND USES THEREOF HOFFMANN LA ROCHE (CH) 2022-04-27 EP disclosed
US-4495183-A ANTIULCER AGENTS- GASTROLINTESTINAL DISORDERS A. H. ROBINS COMPANY, INCORPORATED (US) 1985-01-22 US disclosed
EP-0107866-A2 Trihalomethylpyridine compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-05-09 EP disclosed
US-4447361-A ANTIDEPRESSANT A. H. ROBINS COMPANY, INC. (US) 1984-05-08 US disclosed
EP-0076017-A2 Phenyl substituted pyrido(1,4)benzodiazepines and intermediates therefor A.H. ROBINS COMPANY, INCORPORATED (US) 1983-04-06 EP disclosed
US-4324627-A CHLORINATION OF 3-METHYLPYRIDINE UNDER INFLUENCE OF ULTRA VIOLET LIGHT IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-04-13 US disclosed
US-4317913-A Herbicidal pyridine compounds IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-03-02 US disclosed
EP-0028870-A1 Phenoxypyridine compound IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-05-20 EP disclosed
EP-0021453-A2 2-Chloro-5-trichloromethylpyridine IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-01-07 EP disclosed
EP-0001473-A2 Herbicidal halogenomethyl--pyridyloxy-phenoxy-alkanecarboxylic acids and derivatives, and processes of controlling unwanted plants therewith IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-04-18 EP disclosed
WO-1979000094-A1 HERBICIDAL PYRIDINE COMPOUNDS ICI LTD (GB) 1979-03-08 WO disclosed