Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | TSHR | P16473 | 5/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | KDM4A | O75164 | 1/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859849 | 1.00 | ALDH1A1 (0.73) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL13360008 | 0.90 | TSHR (0.77) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL2492618 | 0.90 | TSHR (0.66) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL9288049 | 0.88 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL27721668 | 0.88 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL20100237 | 0.88 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL27729056 | 0.88 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL30295637 | 0.88 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL4407176 | 0.88 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL8665013 | 0.88 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNAMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953498-A | Diesters and diacids of phenanthrene | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1976-04-27 | — | — | US | disclosed |