Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22411334 | 0.98 | HRH4 (0.52) | HRH4MAPK1KDM4EALDH1A1TSHR | |
| SCHEMBL11848455 | 0.85 | PIK3CA (0.58) | HRH4PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL2276716 | 0.85 | PIK3CA (0.62) | PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL17627938 | 0.82 | HRH4 (0.43) | HRH4PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL17627939 | 0.82 | HRH4 (0.43) | HRH4PIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL30821962 | 0.78 | CYP1A2 (0.47) | HRH4MAPK1KDM4EALDH1A1TSHR | |
| SCHEMBL22411579 | 0.77 | HRH4 (0.49) | HRH4MAPK1KDM4EALDH1A1TSHR | |
| SCHEMBL1089156 | 0.76 | L3MBTL1 (0.69) | MAPK1KDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL3641468 | 0.76 | L3MBTL1 (0.69) | MAPK1KDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL11849344 | 0.76 | GLA (0.52) | HRH4KDM4EALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939268-A | 2,4-Diamino substituted pyridol(3,2-d)pyrimidine as antithrombotic agents | BOEHRINGER INGELHEIM GMBH (DT) | 1976-02-17 | — | — | US | disclosed |