Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.44 |
| ▸ | PRCP | P42785 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11850101 | 0.91 | OPRD1 (0.50) | SIGMAR1PRCPOPRD1KCNH2ADRA2A | |
| SCHEMBL11844053 | 0.90 | OPRD1 (0.45) | SIGMAR1PRCPOPRD1KCNH2ADRA2A | |
| SCHEMBL11849331 | 0.89 | PRCP (0.51) | SIGMAR1PRCPOPRD1 | |
| SCHEMBL11851725 | 0.87 | OPRD1 (0.41) | SIGMAR1PRCPOPRD1KCNH2ADRA2A | |
| SCHEMBL11852685 | 0.87 | PRCP (0.47) | SIGMAR1PRCPOPRD1KCNH2ADRA2A | |
| SCHEMBL11849731 | 0.87 | OPRD1 (0.41) | SIGMAR1PRCPOPRD1KCNH2ADRA2A | |
| SCHEMBL11858336 | 0.87 | OPRD1 (0.47) | SIGMAR1PRCPOPRD1KCNH2ADRA2A | |
| SCHEMBL11849041 | 0.84 | OPRD1 (0.46) | SIGMAR1PRCPOPRD1KCNH2ADRA2A | |
| SCHEMBL11858464 | 0.82 | OPRD1 (0.47) | SIGMAR1PRCPOPRD1KCNH2 | |
| SCHEMBL11844274 | 0.82 | PRCP (0.43) | SIGMAR1PRCPOPRD1KCNH2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3996354-A | 1,3-Dihydro-1'-dimethylphosphinylalkyl-3-phenylspiro(isobenzofuran)s | AMERICAN HOECHST CORPORATION (US) | 1976-12-07 | — | — | US | claimed |