Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.46 |
| ▸ | CA1 | P00915 | 8/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11847503 | 0.87 | CISD1 (0.51) | CA2CA1KDM4EALDH1A1LMNA | |
| SCHEMBL11848400 | 0.84 | CISD1 (0.52) | CA2CA1AKR1C3KDM4EALDH1A1 | |
| SCHEMBL11847155 | 0.82 | KMT2A (0.55) | CA2CA1ALDH1A1LMNAKMT2A | |
| SCHEMBL11845733 | 0.80 | CA2 (0.56) | CA2CA1KDM4EALDH1A1LMNA | |
| SCHEMBL11837682 | 0.79 | PTGER4 (0.55) | CA2CA1KDM4EALDH1A1LMNA | |
| SCHEMBL11787230 | 0.78 | CA2 (0.49) | CA2CA1AKR1C3KDM4EALDH1A1 | |
| SCHEMBL11784477 | 0.78 | CA2 (0.49) | CA2CA1AKR1C3KDM4EALDH1A1 | |
| SCHEMBL2883310 | 0.78 | KDM4E (0.52) | CA2CA1KDM4EALDH1A1LMNA | |
| SCHEMBL11848393 | 0.77 | CA2 (0.43) | CA2CA1KDM4EALDH1A1LMNA | |
| SCHEMBL11795249 | 0.75 | CA2 (0.75) | CA2CA1AKR1C3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |