Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11856469 | 1.00 | HTT (0.43) | HTTSMN1; SMN2HPGDL3MBTL1KDM4E | |
| SCHEMBL883086 | 0.76 | KMT2A (0.53) | HTTSMN1; SMN2HPGDL3MBTL1KDM4E | |
| SCHEMBL16724108 | 0.75 | HPGDS (0.42) | KDM4ENPY5RALDH1A1MAPK1HSD17B10 | |
| SCHEMBL526377 | 0.74 | KDM4E (0.41) | HTTSMN1; SMN2HPGDL3MBTL1KDM4E | |
| SCHEMBL526376 | 0.74 | KDM4E (0.41) | HTTSMN1; SMN2HPGDL3MBTL1KDM4E | |
| SCHEMBL10271343 | 0.73 | KMT2A (0.49) | HTTSMN1; SMN2HPGDL3MBTL1KDM4E | |
| SCHEMBL16724128 | 0.71 | KCNH2 (0.42) | HTTKDM4EMAPTNPY5RALDH1A1 | |
| SCHEMBL9880191 | 0.71 | HPGD (0.41) | HTTSMN1; SMN2HPGDL3MBTL1KDM4E | |
| SCHEMBL11851822 | 0.71 | HPGD (0.37) | HTTSMN1; SMN2HPGDL3MBTL1KDM4E | |
| SCHEMBL7230393 | 0.71 | KDM4E (0.44) | HTTSMN1; SMN2HPGDL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991065-A | ANTIULCER AGENTS, CHEMICAL INTERMEDIATES | JOHN WYETH & BROTHER LIMITED (EN) | 1976-11-09 | — | — | US | disclosed |